Featured:
Systemic chemotherapeutics have limited efficacy in many advanced solid tumours. This study evaluated the safety and tolerability of INT230-6, a unique intratumoural (IT) formulation of cisplatin, vinblastine, and 8-((2-hydroxybenzoyl)amino)octanoate (SHAO), an amphiphilic cell-penetration enhancer.
Presented by Dr. El-Khoueiry at SITC 2020
Paper published in the International Journal of Molecular Sciences, June 24, 2020 (doi.org/10.3390/ijms21124493)
In an interview with Drug Development and Delivery, Lewis H. Bender, MA, MBA, says cancer is a local and systemic disease, and new forms of local treatment, such as intratumoral dosing coupled with systemic immunotherapy, are being explored.
Presentation made at SITC 2019 by Dr. Jacob Thomas, Assistant Professor of Medicine, University of Southern California
Article published online July 16, 2019 in the journal OncoImmunology
Poster: Phase 1/2 Evaluation of Intratumoral INT230-6 for the Treatment of Solid Tumors
Poster presented at SITC 2018