Intensity Therapeutics, Inc., a privately held clinical-stage, biotechnology company developing proprietary cancer immunotherapy products, today announced that the United States Patent and Trademark Office (PTO) issued the Company patent 9,636,406. In addition, the Company noted that the Australian PTO intends to grant Intensity patent 2013318338.
“Intensity’s DfuseRxSM platform has identified our lead drug, INT230-6. This novel product, now in clinical trials, has shown great promise in regressing tumors and extending life in animal models of metastatic cancer,” said Intensity’s President and CEO, Lewis H. Bender. “The newly issued U.S. patent and soon-to-be issued Australian patent allow us to protect our unique technology. The Company now has multiple issued patents and several patent applications in the U.S. and countries around the world. U.S. patent 9,636,406 and near-term issuance of Australian patent 2013318338 increases the likelihood that our products can be secured in important markets.”
INT230-6 is a novel, anti-cancer drug for direct intratumoral injection. The product contains potent anti-cancer agents that disperse throughout tumors and diffuse into cancer cells. INT230-6 was identified from Intensity’s DfuseRxSM platform. In preclinical studies INT230-6 eradicated tumors by a combination of direct tumor kill coupled with recruitment of dendritic cells to the tumor micro-environment that stimulated anti-cancer T-cell activation. INT230-6 provides complete responder animals with long-term, durable protection from multiple re-inoculations of the initial cancer and resistance to other cancers. INT230-6 is being evaluated in clinical study, IT-01. Further information on the human trial can be found at www.clinicaltrials.gov (NCT#03058289).