Category: Publications/Papers/Posters

OncoImmunology July 16, 2019 Intratumorally delivered formulation, INT230-6, containing potent anticancer agents induces protective T cell immunity and memory

Article published on-line July 16, 2019 in the journal OncoImmunology.  https://doi.org/10.1080/2162402X.2019.1625687 Intratumorally delivered formulation, INT230-6, containing potent anticancer agents induces protective T cell immunity and memory. ABSTRACT The benefits of anti-cancer agents extend beyond direct tumor killing. One aspect of cell death is the potential to release antigens that initiate adaptive immune responses. Here, a… Read more »

ASCO 2019 Poster Presentation – Abstract 2602

Safety profile of INT230-6, a novel intratumoral (IT) formulation, during injections into a variety of refractory deep and superficial tumors with evidence of tumor regression and immune activation  

ASCO 2018 Poster Presentation TPS2609

Phase 1/2 trial evaluating intratumoral administration of INT230-6 alone and in combination with an anti-PD1 antibody for advanced malignancies. TPS2609

AACR 2017 Poster

Tumor cell death caused by INT230-6 induces protective T cell immunity.

SITC 2016 Poster

Intratumoral injection of INT230-6 induces protective T cell immunity.

AACR 2016 Poster

A novel immunotherapy, INT230-6, is able to induce high rates of complete and durable response in mice through a cytotoxic T-cell-dependent mechanism

SITC 2015 Poster

Novel Drug, INT230-6 shows strong synergy with anti-PD-1 Antibodies and can induce high complete response rates with T-cell memory response in a colon cancer mouse model

AACR 2015 Poster

INT230-6, a Novel Intratumoral Anticancer Agent, is able to Eradicate Large Established Tumors and Stimulate Potent Antitumor Immunity