Treat Cancer at Any Stage

A New Weapon in the War on Cancer: Kill Tumors and Activate a Systemic Immune Response

Treat locally, act globally. Intensity’s novel intratumoral delivery technology creates drug products that kill cancer cells in a manner that enables immune cells to enter and attack tumors throughout the body. Our vision is to meaningfully extend the lives of patients with metastatic cancer while maintaining their quality of life; for presurgical patients our mission is to avoid disease recurrence.

A New Weapon in the War on Cancer: Kill Tumors and Activate a Systemic Immune Response

Treat locally, act globally. Intensity’s novel intratumoral delivery technology creates drug products that kill cancer cells in a manner that enables immune cells to enter and attack tumors throughout the body. Our vision is to meaningfully extend the lives of patients with metastatic cancer while maintaining their quality of life; for presurgical patients our mission is to avoid disease recurrence.

Tumor
Injection

DfuseRx℠ is our novel proprietary penetration enhancer platform technology that enables therapeutic agents to be injected directly into solid tumors for improved absorption.

Diffusion
Through Tumor

Once injected, DfuseRx enables the injected drug solution to disperse throughout the tumor and increases the drug’s diffusion into cancer cells.

Localized
Cell Death

The absorbed active agents in the injected tumor induce cancer cell death, without disruption of the cell membrane, in a manner that results in an influx of immune cells throughout the tumor.

System-wide
Immune Response

Tumor cell death exposes the immune system to antigens of the patient’s own cancer, inducing a personalized CD4+ and CD8+ T cell response, attacking the site of the former tumor while attacking distal cancer sites.

Increased
Survival

Exploratory analysis of data from a Phase 1/2 trial of relapsed and refractory solid tumor patients with a variety of cancers indicates an association between percent of tumor burden treated and survival.

Technology and Clinical Data

DfuseRxSM is our novel proprietary product discovery technology that enables drug compounds including cytotoxic agents to be injected directly into solid tumors with high absorption. The technology makes use of novel dispersion and cell penetration enhancer molecules that we have identified.
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December 28, 2023

On December 28, the team from Intensity Therapeutics visited the Nasdaq MarketSite in New York’s Times Square. In honor of the occasion, Lewis H. Bender, Founder, President, and CEO, rang the closing bell.

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